Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity related to bortezomib, a proteasome inhibitor Employed in the procedure of a number of myeloma. Its synthesis or analyze is important for ensuring the purity and basic safety in the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor inside the synthesis of abiraterone acetate, a drug Utilized in the treatment of prostate cancer by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-10-1): A crucial compound in the synthesis of imatinib, a drug that targets particular forms of cancer, together with Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers including breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are generally intermediates within the synthesis of gemcitabine, an anti-most cancers drug. Their study is crucial for optimizing the creation course of action and making certain high purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is utilized to treat breast most cancers, and these intermediates are linked to its manufacturing.
Fulvestrant Intermediates: Fulvestrant is really an estrogen receptor antagonist Employed in the therapy of breast cancer. Several intermediates assist in the synthesis of the drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug successful in dealing with PMD cancers which include ovarian, breast, and lung most cancers.
three. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the therapy of colorectal most cancers and little cell lung most cancers.
three-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is linked to the synthesis of adamantane derivatives, that have different purposes, such as antiviral Qualities.
Vildagliptin Intermediates: Utilized in the creation of vildagliptin, an oral drug for variety two diabetic issues that inhibits the enzyme DPP-4 2'-Difluoro-2'-deoxycytidine-3' to regulate blood sugar ranges.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is associated with the synthesis of various gluconic acid derivatives, that happen to be Utilized in foodstuff, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor within the synthesis of canagliflozin, a medication used to manage sort 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).